Potassium alum과 비우식성 감미료의 병용이 Streptococcus mutans의 성장에 미치는 영향
Effect of Potassium Alum and Sugar Substitutes on the Growth of Streptococcus mutans
김윤정, 김강주, 김지영, 송영국, 차정단,
소속 상세정보
김윤정 ( ) - 원광대학교 치과대학 예방치학교실
김강주 ( ) - 원광대학교 구강미생물학교실
김지영 ( ) - 원광대학교 치과대학 예방치학교실
송영국 ( ) - 원광대학교 치과대학 예방치학교실
차정단 ( ) - 전북대학교 구강미생물학교실
KMID : 0355420030270030459
Abstract
Traditionally, Koreans have used potassium alum by mouth rinse when they suffered from stomatitis. This study was carried out to investigate the combined effect of potassium alum with aspartame, sorbitol and xylitol on the growth of Streptococcus mutans (S, mutans). The relative growth ratio of S. mutans JC-2 cultured at different concentrations of potassium alum and different concentrations of aspartame, sorbitol and xylitol was examined. The combined effect of different concentrations of potassium alum with 0.5 and 10.0% of aspartame, sorbitol and xylitol was examined. The lowest minimum inhibitory concentration of potassium alum was 5.0 mg/ml against S. mutans JC-2. The relative growth ratio of potassium alum on S. mutans JC-2 was affected at the concentration of 2.0 mg/ml. The growth of S. mutans JC-2 decreased at the concentration of 10.0% of aspartame and sorbitol. Also, a combination of potassium alum and sugar substitutes was more effective against S. mutans than the use of one sugar substitute alone. The inhibitory effect of potassium alum and sugar substitutes on S mutans may be an important mechanism of caries prevention by potassium alum.
키워드
구강다형연쇄상구규;명반;비우식성 감미료;솔비톨;아스파탐;자일리톨;Aspartame;Potassium alum;Sorbitol;Streptococcus mutans;Sugar substitutes;Xylitol
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